Potent in vitro synergism of fluconazole and berberine chloride against clinical isolates of Candida albicans resistant to fluconazole.

نویسندگان

  • Hua Quan
  • Ying-Ying Cao
  • Zheng Xu
  • Jing-Xia Zhao
  • Ping-Hui Gao
  • Xiao-Feng Qin
  • Yuan-Ying Jiang
چکیده

In vitro interaction of fluconazole and berberine chloride was investigated against 40 fluconazole-resistant clinical isolates of Candida albicans. Synergism in fungistatic activity was found with the checkerboard microdilution assay. The findings of agar diffusion tests and time-kill curves confirmed the synergistic interaction, but no antagonistic action was observed.

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عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 50 3  شماره 

صفحات  -

تاریخ انتشار 2006